For all cities with a population greater than one hundred thousand, Cuidad de Guatemala is closest to Mixco and farthest from Bengkulu. The closest foreign city is Santa Ana and the farthest domestic city is Quetzaltenango. See below for the top 5 closest and farthest cities (domestically, internationally and by continent) and to see which cities, if any, Cuidad de Guatemala is the closest and farthest to. Filter to include all cities over 100k, 500k or 1 million in population.