For all cities with a population greater than five hundred thousand, Dushanbe is closest to Tashkent and farthest from Santiago. The closest foreign city is Tashkent. See below for the top 5 closest and farthest cities (domestically, internationally and by continent) and to see which cities, if any, Dushanbe is the closest and farthest to. Filter to include all cities over 100k, 500k or 1 million in population.