For all cities with a population greater than one million, Esmeraldas is closest to Quito and farthest from Singapore. The closest foreign city is Cali and the farthest domestic city is Guayaquil. See below for the top 5 closest and farthest cities (domestically, internationally and by continent) and to see which cities, if any, Esmeraldas is the closest and farthest to. Filter to include all cities over 100k, 500k or 1 million in population.