For all cities with a population greater than one million, Santa Cruz is closest to Goiânia and farthest from Caloocan. The closest foreign city is Goiânia. See below for the top 5 closest and farthest cities (domestically, internationally and by continent) and to see which cities, if any, Santa Cruz is the closest and farthest to. Filter to include all cities over 100k, 500k or 1 million in population.